Search on: A KINASE ANCHOR PROTEINS 
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Descriptor English:   A Kinase Anchor Proteins 
Descriptor Spanish:   Proteínas de Anclaje a la Quinasa A 
Descriptor Portuguese:   Proteínas de Ancoragem à Quinase A 
Tree Number:   D12.644.360.024.065
D12.776.157.057.002
D12.776.476.024.069
Definition English:   A structurally-diverse family of intracellular-signaling adaptor proteins that selectively tether specific protein kinase A subtypes to distinct subcellular sites. They play a role in focusing the PROTEIN KINASE A activity toward relevant substrates. Over fifty members of this family exist, most of which bind specifically to regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASE TYPE II such as CAMP PROTEIN KINASE RIIALPHA or CAMP PROTEIN KINASE RIIBETA. 
History Note English:   2008 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   52783 
Unique Identifier:   D054758 

Occurrence in VHL:
 

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